Introduction
Nystatin is a widely used antifungal medication that has helped millions treat infections caused by yeast and fungi. Known for its safety and effectiveness, it’s commonly prescribed for oral, skin, and intestinal fungal infections.
What Is Nystatin?
Nystatin belongs to the polyene antifungal class of drugs. It was discovered in the 1950s from a soil bacterium and revolutionized the treatment of fungal diseases. It works by damaging fungal cell membranes, causing the cells to leak and die.
Common Uses
Nystatin is used to treat:
- Oral thrush: Fungal infections in the mouth or throat.
- Skin infections: Such as diaper rash or athlete’s foot.
- Intestinal candidiasis: Yeast growth inside the digestive tract.
It’s available as a cream, ointment, powder, or oral suspension, depending on the infection site.
How Nystatin Works
The drug binds to ergosterol, a key component of fungal cell membranes. This weakens the membrane’s integrity and leads to the destruction of the fungus — without harming human cells.
Side Effects and Safety
Nystatin is generally safe and well-tolerated. Mild side effects may include:
- Stomach upset
- Skin irritation (for topical forms)
- Mild allergic reactions (rare)
Tips for Proper Use
- Always complete the full course of medication.
- Store it at room temperature and away from sunlight.
- Avoid using expired medication, as it may lose effectiveness.